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KMID : 0364819860240010032
Korean Journal of Microbiology
1986 Volume.24 No. 1 p.32 ~ p.37
Regulation of Extracellular Alkaline Protease Biosynthesis in a strain of Streptomyces sp.
Shin Hyoun-seung

Lee Kye-Joon
Abstract
1
In fermentation studies it revealed that Streptomyces sp. SMF 301 started to synthesize extracellular alkaline protease from early exponential phase of cell growth. The biosynthesis of the alkaline protease was greatly induced by skim milk as a sola nitrogen source and further stimulation was observed under inorganic sulphur limited culture. However it was found that the biosynthesis was apparently repressed by NH. and free amino acids, specially by cysteine. It was considered that the strain SMF 301 of Streptomyces sp. would produce¢¥ the alkaline protease for the uptake of sulphur compounds from protein contained in the culture broth.
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